August 2022 eNews

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21^st Annual Wood Hudson Car Show

Hofbrauhaus-Newport

200 Third Street

Newport, KY

Saturday, August 13, 2022

Open To All Makes Of Cars And Trucks

Rain or Shine

Event Program

All Proceeds benefit Wood Hudson Cancer Research Laboratory

Registration:                     9:00-11:30am, $20 entry fee

Split the Pot tickets available throughout the day. Drawing at 2:30pm

Huge Bourbon raffle (30 bottles!) Drawings beginning at 2:00pm

Show:                               DJ music starts at 10:00am

                                         Beverages available after 11:00am

                                         Food available after 11:00am

                                         Judging begins at 10:30am

Awards:                            Trophies given out beginning at 3:00pm

                                         Class A: Pre-1981

                                         Class B: 1981-2004

                                         Class C: 2005-2022

                                         Veterans Trophy

                                         Wood-Hudson Trophy

                                         Best of Show Trophy

To all show entrants: We would like to thank you for participating in our 21^st annual car show benefiting the Wood Hudson Cancer Research Laboratory. If you need anything to make our event a better experience, please see a member of the Ft. Thomas Corvette Club. Enjoy the day!

Hosted by Ft. Thomas Corvette Club

Website: www.ftccvette.us

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UREP “Science Day” 2022

            August 10^th marked “Science Day” when the Undergraduate Research Education Program (UREP) students from Thomas More University (TMU), Mount St. Joseph University (MSJ), Xavier University (XU), Craft Academy at Morehead State University (MSU) Gatton Academy at Western Kentucky University (WKU), and Conner High School gave their final report on their projects to design an experiment to understand one of the “Provocative Questions” proposed by the National Institutes of Health.  Two students, Caroline Klug (UC) and Sophie McVay (TMU) designed experiments to answer the question “How does intermittent fasting affect cancer incidence, treatment response, or outcome?” Three students, Alexis Evangelou (MSJ), Erin Olakanmi (MSJ) and Heng Yang (Conner H.S.) tackled the question “What are the underlying causes of the unexplained rising incidence in certain early-onset cancers?” The question of “What methods can be developed to effectively study small or rare populations relevant to cancer research?” was addressed by Brody Johnson (Gatton Academy/WKU).  “How can cancer cachexia be reversed?” was a problem that Caden Togrul (XU), Megan Poynter (MSJ) and Hannah Stanley (Craft Academy/MSU) studied. Jonathan Scherff (MSJ) designed an experiment to elucidate “How do selective pressures affect cell competition and cooperation during cancer initiation or development?”  “What methods can be developed to integrate patient-generated health data into electronic health records?” were discussed by Kaylee Ferguson (MSJ).

          These presentations were the third presentation each student prepared this summer.  Each student also reported on a recent peer-reviewed journal article and also gave a lecture on one chapter in “Principles of Cancer Biology.”  Thanks to Prof. Diane Willkening Gilb, who organized the Google Classroom and Connect assignments, students had the opportunity to work with on-line resources, including technical videos, and review chapters in an on-line Anatomy and Physiology textbook that were complementary to the chapters in the textbook “Principles of Cancer Biology” that each student was given at the start of the summer program.

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Fall 2022 UREP opportunities with Dr. Erik A. Bey at

Wood Hudson Cancer Research Laboratory

     Breast cancer is the second leading cause of cancer related deaths amongst U.S. women. Metastatic breast cancers, especially triple negative breast cancers, continue to decrease the overall survival rate of breast cancer patients. Thus, new strategies to effectively eliminate primary and metastatic breast cancer are desperately needed.

     Cancer cells have adaptive strategies to thwart oxidative stress produced in the tumor microenvironment. This amelioration of reactive oxygen species is in part accomplished through overexpression or mutations in genes that regulate oxidative stress pathways.

     Our hypothesis is that altering the expression of oxidative stress genes in breast cancers including triple negative breast cancers, will also affect their ability to become tumorigenic and increase their sensitivity to chemotherapy.

    Students working with Dr. Bey will have the opportunity to learn basic tissue culture techniques, wet lab set up, survival and colony forming assays, western blotting, DNA damage assays, microscopy and numerous other techniques. Students may also have the opportunity to prepare their data for manuscript publication and research presentations such as posters for local and national meetings.

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